Background: The rapid development of genetic and genomic
technologies, such as next-generation sequencing and genome
editing, has made disease treatment much more precise and
effective. The technologies’ value can only be realized by the
aggregation and analysis of people’s genomic and health data.
However, the collection and sharing of genomic data has many
obstacles, including low data quality, information islands,
tampering distortions, missing records, leaking of private data,
and gray data transactions. Objective: This study aimed to prove
that emerging blockchain technology provides a solution for the
protection and management of sensitive personal genomic data
because of its decentralization, traceability, encryption
algorithms, and antitampering features. Methods: This paper
describes the case of a blockchain-based genomic big data platform,
LifeCODE.ai, to illustrate the means by which blockchain enables
the storage and management of genomic data from the perspectives of
data ownership, data sharing, and data security. Results:
Blockchain opens up new avenues for dealing with data ownership,
data sharing, and data security issues in genomic big data
platforms and realizes the psychological empowerment of individuals
in the platform. Conclusions: The blockchain platform provides new
possibilities for the management and security of genetic data and
can help realize the psychological empowerment of individuals in
the process, and consequently, the effects of data self-governance,
incentive-sharing, and security improvement can be achieved.
However, there are still some problems in the blockchain that have
not been solved, and which require continuous in-depth research and
innovation in the future.
This is the abstract only. Read the full article on the JMIR site.
JMIR is the leading open access journal for eHealth and healthcare
in the Internet age.
Source: All – Medical Journals
Application of a Blockchain Platform to Manage and Secure Personal Genomic Data: A Case Study of LifeCODE.ai in China